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Hironobu Akino Selected Research

imidafenacin

5/2015Add-on anticholinergic therapy for residual nocturia in patients with lower urinary tract symptoms receiving α1-blocker treatment: a multi-centre, prospective, randomised study.
4/2014Factors influencing patient satisfaction with antimuscarinic treatment of overactive bladder syndrome: results of a real-life clinical study.
7/2013Antidiuretic effect of antimuscarinic agents in rat model depends on C-fibre afferent nerves in the bladder.
6/2011Antimuscarinics suppress adenosine triphosphate and prostaglandin E2 release from urothelium with potential improvement in detrusor overactivity in rats with cerebral infarction.

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Hironobu Akino Research Topics

Disease

11Cerebral Infarction
08/2017 - 01/2002
6Overactive Urinary Bladder (Overactive Bladder)
04/2014 - 04/2004
6Prostatic Neoplasms (Prostate Cancer)
01/2014 - 01/2002
5Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2017 - 05/2003
5Lower Urinary Tract Symptoms
05/2015 - 01/2013
5Neoplasms (Cancer)
03/2014 - 02/2002
4Spinal Cord Injuries (Spinal Cord Injury)
11/2016 - 02/2004
4Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2015 - 10/2008
3Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
01/2019 - 11/2007
3Nocturia
05/2015 - 07/2010
2Ataxia (Dyssynergia)
11/2016 - 02/2004
2Polyuria
05/2015 - 07/2013
2Renal Cell Carcinoma (Grawitz Tumor)
03/2014 - 09/2011
2Neoplasm Metastasis (Metastasis)
05/2013 - 01/2013
1Hypertension (High Blood Pressure)
11/2015
1Seminoma
04/2015
1Pain (Aches)
04/2015
1Urinary Incontinence
03/2015
1Constipation
04/2014
1Cysts
03/2014
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2013
1Cystitis
03/2012
1Interstitial Cystitis (Interstitial Cystitis, Chronic)
03/2012
1Carcinoma (Carcinomatosis)
03/2011
1Brain Diseases (Brain Disorder)
11/2010
1Inflammation (Inflammations)
02/2010
1Urinary Retention
11/2007
1Urinary Bladder Neoplasms (Bladder Cancer)
06/2004

Drug/Important Bio-Agent (IBA)

6Muscarinic AntagonistsIBA
04/2014 - 11/2005
5resiniferatoxinIBA
01/2019 - 11/2005
4imidafenacinIBA
05/2015 - 06/2011
3Tolterodine Tartrate (Detrol)FDA Link
04/2014 - 11/2005
2salicylhydroxamic acid (SHAM)IBA
01/2019 - 12/2007
2naftopidilIBA
01/2019 - 01/2006
2Nerve Growth Factor (NGF)IBA
08/2017 - 11/2010
2Halothane (Fluothane)FDA Link
08/2017 - 05/2003
2Cholinergic Antagonists (Anticholinergics)IBA
05/2015 - 03/2015
2Solifenacin SuccinateFDA Link
04/2014 - 12/2011
2Tamsulosin (Flomax)FDA LinkGeneric
01/2014 - 12/2011
2Prednisolone (Predate)FDA LinkGeneric
09/2013 - 05/2013
2Docetaxel (Taxotere)FDA Link
09/2013 - 05/2013
2Paclitaxel (Taxol)FDA LinkGeneric
05/2013 - 03/2011
2Carboplatin (JM8)FDA LinkGeneric
05/2013 - 03/2011
2Cisplatin (Platino)FDA LinkGeneric
01/2013 - 03/2011
2Adenosine Triphosphate (ATP)IBA
03/2012 - 06/2011
2Pharmaceutical PreparationsIBA
06/2011 - 05/2003
2Cyclooxygenase InhibitorsIBA
01/2011 - 02/2010
2Messenger RNA (mRNA)IBA
05/2003 - 01/2002
1CationsIBA
01/2019
1Adenosine (Adenocard)FDA LinkGeneric
01/2019
1Nylons (Nylon)IBA
08/2017
1SaltsIBA
11/2015
1Type A Botulinum Toxins (Botox)FDA Link
03/2015
1Adrenergic Antagonists (Antiadrenergic Agents)IBA
03/2015
1Dutasteride (Avodart)FDA Link
03/2015
1Tadalafil (Cialis)FDA Link
07/2014
1oxybutynin (Tavor)FDA LinkGeneric
04/2014
1propiverineIBA
04/2014
1Acetates (Acetic Acid Esters)FDA Link
03/2014
1silodosinFDA Link
01/2014
1Prostate-Specific Antigen (Semenogelase)IBA
05/2013
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
05/2013
1Hormones (Hormone)IBA
05/2013
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
05/2013
1Etoposide (VP 16)FDA LinkGeneric
01/2013
1Angiotensin Receptor AntagonistsIBA
01/2013
1Ion Channels (Ion Channel)IBA
03/2012
1rho-Associated KinasesIBA
03/2012
1Acetylcholine (Acetylcholine Chloride)FDA Link
03/2012
1Therapeutic UsesIBA
09/2011
1Sunitinib (Sutent)FDA Link
09/2011
1fosfestrol (Kyorin)FDA Link
06/2011
1Dinoprostone (PGE2)FDA Link
06/2011
1GemcitabineFDA Link
03/2011
1ProstaglandinsIBA
11/2010
1Substance PIBA
11/2010
1Prostaglandins FIBA
11/2010
1Prostaglandins EIBA
11/2010
1MelatoninIBA
07/2010
1Proteins (Proteins, Gene)FDA Link
02/2010
1Adrenergic Receptors (Adrenergic Receptor)IBA
10/2008
1AtropineFDA LinkGeneric
12/2007
1Glutamate Receptors (Glutamate Receptor)IBA
04/2004
1Opiate AlkaloidsIBA
02/2004
1kappa Opioid Receptors (kappa Opioid Receptor)IBA
02/2004

Therapy/Procedure

7Therapeutics
11/2016 - 01/2002
5Drug Therapy (Chemotherapy)
04/2015 - 03/2011
2Anesthesia
08/2017 - 05/2003
2Combination Drug Therapy (Combination Chemotherapy)
09/2013 - 03/2011
2Castration
09/2013 - 05/2013
2Prostatectomy (Retropubic Prostatectomy)
05/2013 - 01/2002
1Ligation
01/2019
1Orchiectomy (Orchidectomy)
04/2015
1Withholding Treatment
03/2015
1Brachytherapy
01/2014
1Renal Dialysis (Hemodialysis)
09/2013
1Adrenalectomy
01/2013
1Denervation
03/2012
1Conservative Treatment
01/2010
1Cystectomy
06/2004